Researchers have recently devised a novel approach to reduce T cell fatigue even in cancers that are resistant to clinically approved immunotherapies.


About T cells

  • T cell is a type of white blood cell.
  • It is also called T lymphocyte and thymocyte.
  • T cells are part of the immune system and develop from stem cells in the bone marrow.
  • They help protect the body from infection and may help fight cancer.
  • There are two main types —
      • Cytotoxic T-cells — Destroy infected cells.
      • Helper T-cells   Send signals that direct other immune cells to fight infection.
  • Rather than generically attack any antigens, T cells circulate until they encounter their specific antigen.
  • T-cells have many identical T-cell receptors that cover their surfaces and can only bind to one shape of antigen.
  • When a T-cell receptor fits with its viral antigen on an infected cell, the Killer T-cell releases cytotoxins to kill that cell.