IIT Jodhpur, Dystrophy Annihilation Research Trust (DART) and AIIMS Jodhpur are working on developing an affordable treatment for a rare and incurable genetic disorder called Duchenne Muscular Dystrophy (DMD).

 

About DMD

  • It is the most common and fatal type of muscular dystrophy marked by progressive muscle degeneration and weakness due to alterations of a protein called “dystrophin” that helps keep muscle cells intact.
  • Patients (usually children) have reduced bone density and an increased risk of developing fractures.
  • India has over 5 lakh patients in the country suffering from DMD and the condition is predominantly seen in boys, but in rare cases, it can also affect girls.
  • It can begin as early as age 2 or 3, first affecting the proximal muscles (those close to the core of the body) and later affecting the distal limb muscles (those close to the extremities).
  • Symptoms  — Enlargement of calves, a waddling gait, and lumbar lordosis (an inward curve of the spine).
  • The current therapeutic options available to treat DMD are minimal and highly expensive treatment and are mostly imported from abroad.